Rasmussen CollegeNURSING 2047Pharmacology Exam 1 Study Guide Drugs that PRODUCE a response? o Agonist Drugs that PREVENT a response? o Antagonist Therapeutic WINDOW is what? o Level of th... e drug between minimal effective concentration in the plasma for obtaining desired drug response and the minimal toxic concentration The time it takes for ½ of the drug concentration to be eliminated from the body is called? o Half life What is a patient on two highly protein bound drugs at risk for o Accumulation and toxicity o A decreased responsiveness over the course of therapy which may lead to the need to increase dosages to attain the same effect tolerance What is it called for drugs to share many common features o Classification or class What makes drugs fit into the same “class” o Related by chemical structure o Work in the same way o Used for the same purpose Another name for antagonist? o Adrenergic blocker Who do you not give antagonist or adrenergic blocker to? o Asthma client Beta blockers commonly seen in what clients? o Hypertension Antagonist suffix o LOL Antagonist S/S o Decreased HRo Rest and digest o Bronchospasm Agonist S/S o Increased HR, Fight or flight, Vasoconstriction, Increase blood sugar Before administering antagonist what do you check o HR and BP Cholinergic o Salivate, Lacrimation, Urinate, Defecate, Decreased weight Anticholinergic o Can’t see, pee, spit, poop, and increase HR What type of drug is Reglan? o Cholinergic How do you treat cholinergic crisis o Atropine Cholinergic crisis S/S o Flushing, sweating, nausea, ab cramping Anticholinergic drugs are contraindicated in who? o Coronary artery disease (increase HR) o GI obstruction (constipation) o Supraventricular tachycardia (increase HR) CNS stimulant drugs are contraindicated in who? o Coronary artery disease (cause vasoconstriction=heart attack) o Hypertension (additive hypertension=stroke) Hemorrhagic stroke o Increase BP o Increase HR o Increased RR o Unresponsive to deep pain Anorexiants can lead to what? o 16x greater risk for stroke Most common side effects of Ritalin o Irritability o Insomnia Weight loss Decrease appetite Benzodiazepines increase activity to what neurotransmitter (PAM & LAM) o GABA Reversal to benzodiazepines o Flumazenil ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::MORE IN THE ATTACHMENT:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: [Show More]
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