*NURSING > STUDY GUIDE > NR 508 Advanced Pharmacology Week 4 Midterm Filled Outline + Chart (2 Versions Study Guide). Chamber (All)

NR 508 Advanced Pharmacology Week 4 Midterm Filled Outline + Chart (2 Versions Study Guide). Chamberlain College of Nursing

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NR 508 Week 4 Midterm Filled Outline + Chart (2 Versions) Chapter 1: The Role of the Advanced Practice Nurse as Prescriber Roles and responsibilities of APRN prescribers Clinical judgement in Pre... scribing Chapter 2: Review of Basic Principles of Pharmacology Metabolism: Metabolism & Half Life Drug Responses Receptors: agonists, antagonists Pharmacokinetics: Absorption, Distribution, Protein Binding, Metabolism (including first-pass and Phase I and II) Cytochrome P450 metabolism Excretion: Renal, Biliary, Other (eg for volatile drugs) Chapter 3: Rational Drug Selection Process of rational drug prescribing: 6 Steps proposed by WHO Patient education Monitor effectiveness Drug, Patient, and Provider factors that influence drug selection Influences on Rational Prescribing: Pharmaceutical Promotion Chapter 4: Legal and Professional Issues in Prescribing New Drug Approval process including Clinical Phases. S. FDA Regulatory Jurisdiction: official labelling vs off-label use of drugs Chapter 5: Adverse Drug Reactions Mechanistic Classification of ADRs including Types of Immune-Mediated ADRs and Types A-F Common Causes of ADRs: Risk Factors, including common drugs involved and which cause skin reactions Time-Related Classification of ADRs including drugs associated with withdrawal symptoms Dose-Related ADRs classification. Chapter 6: Factors that Foster Positive Outcomes Overview of nonadherence Keys to effective patient education Health and Cultural beliefs Health Literacy Complexity of Drug Regimen and Polypharmacy Simplifying the Regimen Communication Difficulties Chapter 9: Nutrition and Nutraceuticals Nutrient-Drug Interactions (eg warfarin and vit K) Influence of Diet on Pharmacokinetics of Drugs: infants and children women of child bearing age pregnant women vegans older adults those not exposed to sunlight or with dark skin alcoholics patients taking isoniazid (INH) Nutraceuticals: Vitamin that is teratogenic in excessive amounts Vitamin that is useful for migraine prophylaxis Chapter 12: Pharmacoeconomics Know what Pharmacoeconomics is Impact of Cost: Direct and Indirect Chapter 13: Over-the-counter Medications OTC Medication characteristics and regulation OTC Medication Sales Hazards of OTC Self-Medication Adverse Effects of OTC Self-Medication Drug Interactions: antacids, anticholinergics, CNS Depressants, NSAIDS and ASA Abuse of OTC Medications: Combat Methamphetamine Epidemic Act Patient Education Regarding OTC Medications Chapter 14 Drugs Affecting the Autonomic Nervous System Pharmacodynamics of Alpha2 Agonists Pharmacodynamics of Beta Blockers, adverse effects, what happens with abrupt withdrawal of Beta Blockers? Pharmacokinetics: Beta blockers Phamacotherapeutics: precautions and Contraindications of beta blockers Adverse Drug Reactions Clinical Uses and Dosing of Beta Blockers pg 194-195 see the table to review! Muscarinic Agonists: Pharmacodynamics, MOA, treatment uses, Chapter 15 Drugs Affecting the Central Nervous System Anorexiiants Iminostilbenes Succinimides:. Drugs That Affect GABA Tricyclic Antidepressants (TCA Monoamine Oxidase Inhibitors(MAOIs): SSRI Chapter 28 Chronic Stable Angina and Low Risk Unstable Angina Additional Patient Variables: Concomitant Diseases MI HF HTN Hypercholesterolemia Peripheral vascular disease Diabetes Mellitus Asthma Erectile Dysfunction Beta Blocker-diabetes Mellitus Chapter 36: Heart Failure Indications for heart failure drugs by stage First line drugs of choice for heart failure MOA of ACEIs that benefit heart failure Indications for use of BBs in patients with heart failure Drugs that increase life expectancy in patients with heart failure Digoxin indications and adverse reactions Drugs contraindicated in heart failure Drugs for managing heart failure during pregnancy Patient monitoring of HF Indications to use anticoagulant therapy Patient education Chapter 40 Hypertension Classes of drugs used and their MOAs: Nitrates, BBs, CCBs, ACEIs What drugs increase myocardial oxygen supply Causes of hypertension Which drugs treat hypertension & BPH, MI, Heart Failure African Americans. Chapter 14: Drugs Affecting the Autonomic Nervous System Adrenergic Agonists Alpha2 Agonists: Central Alpha1 Antagonists Combined Alpha- and Beta-Adrenergic Antagonists Name of drugs in this category Indications for use Pharmacodynamics Precautions ADRs Drug interactions of carvedilol clinical use: HTN, CHF (what stage of CHF is an indication to use?); Withdrawal of alpha-beta blockers concomitant diseases Monitoring Cholinergic Agonists Chapter 15: Drugs Affecting the Central Nervous System Anorexiants Anticonvulsants Benzodiazepines Uses including status epilepticus Chapter 29: Anxiety and Depression Classes of Medications ADRs Special Populations Outcome Evaluation Clinical Pearls Chapter 43: Smoking Cessation Rational Drug Selection Tobacco-cessation therapies [Show More]

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