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NUR2407 / NUR 2407 Pharmacology Exam 2 Blueprint | Rated A | Latest 2020 / 2021 | Rasmussen College

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NUR2407 / NUR 2407 Pharmacology Exam 2 Blueprint | Rated A | Latest 2020 / 2021 | Rasmussen College Review the following medications know the indication for use, patient education, side effects, ad... verse effects drug to drug and/or drug to food interactions. Also know any associated therapeutic levels (if given) of medications • Psychiatric disorders o Schizophrenia  Symptoms • Positive- psychotic symptoms, delusions, Hallucinations, disorganized speech, disorganized behavior, catatonic behavior. • Negative- removal of normal processes. Decreased emotions, loss of interest (flat affect- inappropriate response) Alogia (poverty of speech)Avolition (decreased motivation). • Cognitive- Affects – memory, learning, understanding. Subtle; difficult to notice.  Psychosis • Antipsychotic medications ( DOPEAMINE BLOCKERS) o Typical o Introduced in 1952 o Phenothiazines o Nonphenothiazines- adverse effects – decrease in WBC count increasing risk of infection. o Multiple side effects o o Atypical o 1960s—available 1971 in Europe o Clozapine (Clozaril) first atypical – less likely to have extrapyramidal symptoms. o Came later in US d/t hemotology issues (1990) o Decreased side effects o o • Adverse effects --first generation vs. second generation o Extrapyramidal symptoms (EPS)  Resembles symptoms of parkinsonism  Stooped posture  Masklike facies  Rigidity  Tremors at rest  Shuffling gait  Pill-rolling motions of hands/fingers  Bradykinesia o Acute dystonia  Muscle spasms in face, tongue, neck, back  Grimacing  Abnormal or upward eye movements  Laryngeal spasms  Relived by benztropine -- anticholinergic o Akathisia  Trouble standing still  Restless  Pacing  Constant motion (rocking)  Relived by benzodiazepine or beta-blocker (Ativan or propranolol) o Tardive dyskinesia (TD)  Serious adverse reaction with typical antipsychotics taken > 1yr o Higher prevalence in cigarette smokers o Characteristics are o Protrusion/rolling tongue o Sucking & smacking movements of lips o Chewing motion o Involuntary movement of body & extremities o o Neuroleptic malignant syndrome (NMS) o Psychotropic washout period – MAOI’s make sure that they are washed out of your system before starting another med. (2 week period) o Medications (provide interpreter for patients who do not have English as a first language. Advise patients to take as directed.  Chlorpromazine- Strong sedative effect  Decreased blood pressure  Orthostatic hypotension [Show More]

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