*NURSING > EXAM > NR 565/NR565 WEEK 7 & 8 FINAL EXAM STUDY GUIDE, CHAMBERLAIN(latest) 2022 update (All)
NR 565 Exam Final Study Guide Antacids: weak bases that react with hydrochloric acid to form salt & water. o Used in the treatment of Hyperacidity, GERD, PUD, hyperphosphatemia, and calcium defi... ciency o Contain combinations of metallic cation (aluminum, calcium, magnesium, and sodium) and basic anion (hydroxide, bicarbonate, carbonate, citrate, and trisilicate) Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics o Neutralize Gastric Acidity (causes ^pH of the stomach and duodenal bulb) o Inhibit proteolytic activity of pepsin o Increase lower esophageal sphincter tone o Acid-neutralizing capacity ANC varies between products expressed in mEqs o If ingested in a fasting state, antacids reduce acidity for approximately 20 to 40 minutes o If taken 1 hr after a meal, acidity is reduced for 2 to 3 hrs o A second dose taken after a meal maintains reduced acidity for more than 4 hrs after the meal o The action of antacids occurs locally in the GI tract with minimal absorption, minimal metabolism o ALL antacids are contraindicated in the presence of severe abdominal pain of unknown cause, especially if accompanied by fever -HIGH SODIUM content: pts w/ HTN, CHF, marked renal failure, or on low-sodium diets need to use low sodium preparation -Concurrent administration with enteric-coated drugs, destroys the coating= alters absorption, ^ the risk for adverse effects -Administrations should be separated by at least 2 hours to decrease drug/drug interactions 1. Calcium based antacids: TUMS, Caltrate, Calcarb Prescribed to treat calcium deficient states, i.e. chronic renal failure, post-menopause, and osteoporosis Used to bind phosphates in CRF Require Vitamin D for absorption from the GI tract Excreted mainly in feces, 20% in urine ADR: Contraindicated in the presence of hypercalcemia and renal calculi Can cause constipation- increase bulk, fluids and mobility, stool softener Administered 30min- 1hr on empty stomach or 3hr after meals Should not be administered with food containing large amounts of oxalic acid (spinach, rhubarb), or phytic acid (bran, cereals), they decrease the absorption of calcium Taking w/ foods containing phosphorus (milk, dairy) [Show More]
Last updated: 1 year ago
Preview 1 out of 37 pages
Buy this document to get the full access instantly
Instant Download Access after purchase
Add to cartInstant download
We Accept:
Connected school, study & course
About the document
Uploaded On
Sep 11, 2022
Number of pages
37
Written in
This document has been written for:
Uploaded
Sep 11, 2022
Downloads
0
Views
30
In Browsegrades, a student can earn by offering help to other student. Students can help other students with materials by upploading their notes and earn money.
We're available through e-mail, Twitter, Facebook, and live chat.
FAQ
Questions? Leave a message!
Copyright © Browsegrades · High quality services·