NR 507 MIDTERM STUDY GUIDE| FOR GRADE A+

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NR 507: MIDTERM REVIEW Hematology Hematopoiesis: - The process of blood cell production -Constant through life to replace Red Blood Cells that grow old and die, are killed by disease, o... r are lost due to bleeding -Occurs in liver and spleen of fetus -Occurs in bone marrow after birth -2 stages: 1. Proliferation (mitotic division) 2. Maturation (differentiation) -Bone marrow: red (hematopoietic/active) & yellow (fatty/inactive) Hematopoietic stem cells (HSCs)- All blood cells are created from HSCs -signaled to undergo differentiation (by cytokines and chemokines, growth factors) to form RBC, WBC, & platelets • Lymphoid: T cell (T-lymphocyte) & B cell (B-lymphocyte) • Myeloid: Monocyte & Granulocytes (WBCs) • Erythrocyte (RBC) • Megakaryocyte (Platelets) Mesenchymal stem cells-develop into osteoclasts, fibroblasts, & adipocytes <clip_image001.png> Erythropoietin: -hormone that stimulates erythrocyte production [Show More]

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