Sinchita Roy-Chowdhuri Paul A. VanderLaan John M. Stewart Gilda da Cunha Santos Editors Molecular Diagnostics in Cytopathology A Practical Handbook for the Practicing Pathologist

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Sinchita Roy-Chowdhuri Paul A. VanderLaan John M. Stewart Gilda da Cunha Santos Editors Molecular Diagnostics in Cytopathology A Practical Handbook for the Practicing Pathologist Part I Ove... rview of Molecular Cytopathology 1 Introduction: Overview of Current Molecular Diagnostic Testing on Cytology Samples . . . . . . . . . . 3 Michael H. Roh and Rashmi Kanagal-Shamanna Part II Laboratory Processing: Practical Considerations 2 The Cytology Specimen and Preparations: Advantages and Limitations . . . . . . . . . . . . . . . . . . . . 23 Gilda da Cunha Santos and Mauro Ajaj Saieg 3 Sample Acquisition and Test Requisition . . . . . . . . . 39 Ross A. Miller and Ashwyna Sunassee 4 Pre-analytic Workflow and Specimen Evaluation . . 61 John M. Stewart 5 DNA-Based Sequencing Assays . . . . . . . . . . . . . . . . . 83 Pasquale Pisapia, Miriam Cieri, Francesco Pepe, Umberto Malapelle, and Giancarlo Troncone 6 RNA-Based Assays . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 Umberto Malapelle, Pasquale Pisapia, Miriam Cieri, Francesco Pepe, and Giancarlo Troncone 7 FISH Testing of Cytology Specimens: Pre-analytic, Analytic, and Post-analytic Considerations . . . . . . . . 121 Karen D. Tsuchiya, Laura J. Tafe, and Julia A. Bridge 8 Molecular Cytopathology Correlations: Interpretation of Molecular Diagnostic Results . . . . 161 Sinchita Roy-Chowdhuri Part III Clinical Relevance 9 Human Papillomavirus (HPV) Testing of Head and Neck Cancers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181 Eleanor Russell-Goldman and Jeffrey F. Krane 10 Human Papillomavirus (HPV) Testing on Cervical Cytology Specimens . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 Ming Guo 11 Molecular Diagnostics in Lung Cytology . . . . . . . . . . 223 Paul A. VanderLaan 12 Molecular Diagnostics in Thyroid Cytology . . . . . . . 249 Michiya Nishino 13 Molecular Diagnostics in Breast Cytology . . . . . . . . 301 Liza M. Quintana 14 Molecular Diagnostics in Salivary Gland Cytology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 Esther Diana Rossi and Zubair W. Baloch 15 Molecular Diagnostics in Pancreatic and Biliary Cytology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 Mingjuan Lisa Zhang and Martha Bishop Pitman 16 Fluorescence In Situ Hybridization (FISH) Testing in Urinary Tract Cytology. . . . . . . . . . . . . . . . 377 Güliz A. Barkan and Stefan E. Pambuccian 17 Molecular Diagnostics in Hematologic Malignancies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405 Rashmi Kanagal-Shamanna 18 Molecular Diagnostics in Bone and Soft Tissue Tumors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425 Vickie Y. Jo and Xiaohua Qian 19 Molecular Diagnostics in Pediatric Cytopathology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 491 Maren Y. Fuller and Sara E. Monaco 20 Molecular Cytopathology: Final Thoughts and Future Directions . . . . . . . . . . . . . . . . . . . . . . . . 517 Sinchita Roy-Chowdhuri Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . [Show More]

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