NURS 4380 PATHOPHYSIOLOGY,PHARMACOLOGY & PHYSICAL ASSESSMENT FINAL EXAM STUDY GUIDE Latest 2021/2022

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NURS 4380 PATHOPHYSIOLOGY,PHARMACOLOGY & PHYSICAL ASSESSMENT FINAL EXAM STUDY GUIDE Latest 2021/2022 Basics of Antibiotics (13) 1. Define selective toxicity as it applies to the general mechanis... ms by which antibiotics work against invading pathogens but not against host cells. o Selective toxicity means that the drug interferes with necessary microbial biochemical processes. The pathogen is a prokaryote, while the host (us) is eukaryote, so their genetic makeup is different. • Explain disruption of bacterial cell wall (Ex: Penicillin and cephalosporins) ➢ Prokaryotes (Bacteria) are encased in a rigid cell wall ➢ The protoplasm within this wall has a high concentration of solutes, making osmotic pressure within high ➢ Without this cell wall, bacteria would absorb water, swell, and then burst [Show More]

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