Chemistry > Lab Report > CHEM 272-Lab 10 Report-GRADED A (All)

CHEM 272-Lab 10 Report-GRADED A

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Experiment 10: Kyle’s Aspirin Abstract: The purpose of this experiment was to find out what exactly is the active ingredient in Kyle’s aspirin. In order to do this, the concentration of acetyls... alicylic acid in Kyle’s aspirin needs to be determined. The identity of Kyle’s aspirin was C (may have been B, may have been a switch up in labels). The hypothesis of the experiment was that Kyle needed to take a larger dosage of internet aspirin because the concentration of his aspirin may not be enough. If Kyle's internet aspirin contains a lower concentration of its active ingredient than the Bayer pills, then this explains why his dosage would be doubled A series of titrations of Kyle’s aspirin, pure acetylsalicylic acid, and a Bayer were all completed using NaOH as the titrant. For each of these titrations, the pH was tracked with a pH probe. For the Bayer aspirin tablet (325 mg), the end point was at 14.40 mL, Kyle’s aspirin at 8.0 mL, and for the pure compound. The pKa for the Bayer tablet is around 5.35. The pKa of the pure acetylsalicylic acid is around 5.27. The pKa of Kyle’s tablet is 5.77. Since these Kyle’s aspirin pKa is close to the Bayer tablet and pure acetylsalicylic acid, it is safe to assume that acetylsalicylic acid was the active ingredient within Kyle’s aspirin. The mass percent of acetylsalicylic acid in Kyle’s Aspirin was 47.0% and for the Bayer tablet it was 87.7% (based off the label) and 84.2% (based off what was measured on scale). This just shows how Kyle’s aspirin required him to take it twice the normal dosage because his aspirin is less concentrated [Show More]

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