NR283 Pathophysiology Exam 3 Review .Chamberlain College of NursingSchool name NR 283 .

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NR283 Pathophysiology Exam 3 Review Chapter 19 Alterations of Hormonal Regulation - Addison’s disease – (Adrenal Insufficiency)- - - Autoimmune disorder where body creates antigens that attack ... the adrenal glands - - decrease in hormones in adrenal cortex such as corticosteroid and mineralocorticoid synthesis and elevated levels of ACTH (loss of negative feedback). - -More then 90% of adrenocortical tissue is destroyed causing clinical manifestations. - - No adrenal glands working resulting in hypocortisolism (low levels of cortisol) and hypoaldosteronism - - Clinical Manifestations: Weakness, fatigue hypotension, hyperkalemia (^K), hypoglycemia, elevated ACTH, skin changes (hyperpigmentation and vitiligo) may occur [Show More]

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