PATHOLOGY POOLED MCQS FOR GRE/GAT/SUBJECT 2023 WITH VERIFIED ANSWERS

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Subject (1-650) MCQ’s Answer Key 1) Which of the following represents an increase in size of a cell in response to increased demand or hormonal stimulation? A A. Hypertrophy B. Hyperplasia ... C. Metaplasia D. Anaplasia 2) Which of the following sequelae of ischemia would be considered an irreversible cellular injury? C A. cellular acidosis B. fatty metamorphosis C. rupture of lysosomes D. None of these 3) Which of the following would typically result in liquifactive necrosis? A A. cerebral infarction from middle cerebral artery thrombosis B. liberation of pancreatic enzymes into peritoneum due to acute pancreatitis C. myocardial infarction from coronary thrombosis D. None of these 4) Frozen section evaluation of a lymph node biopsy from the neck of an old dog shows granulomatous inflammation with large areas of necrosis. Which of the following would be most important to do? C A. cell surface markers for lymphocyte phenotyping B. chromosomal analysis by karyotyping C. cultures for acid fast bacilli and fungi D. None of these 5) A buffalo with immunodeficiency state presents with weight loss and cough. Chest x-ray shows pulmonary infiltrates. A tuberculin skin test shows no reaction. Which of the following interpretations is most correct? C A. he does not now have and never has had tuberculosis B. he does not now have tuberculosis, but may have in the past C. he may or may not have tuberculosis D. None of these 6) Each of the following is an example of apoptosis except: C A. deletion of autoreactive T cells from thymus B. destruction of hepatocytes in chronic hepatitis C. stroke caused by thrombosis of middle cerebral artery D. None of these 7) Orchiectomy (removal of testes) would be expected to cause which of the following in prostatic epithelium in a old dog: A A. atrophy B. fatty change C. Cell swelling D. None of these 8) One year after an intestinal operation the palpation of the incision site shows it to be firmer than surrounding. This is predominantly due to: A A. increased density of collagen fibers B. increased density of elastin fibers C. increased number of regenerating cells D. None of these 9) Amyloid consists of: A A. extracellular deposits of altered protein in a Beta-pleated sheet B. extracellular accumulations of damaged collagen fibrils C. denatured proteins D. None of these 10) Each of the following increases the risk of thrombosis EXCEPT: B A. endothelial injury B. factor XIII deficiency C. venous stasis D. None of these 11) Teratomas are best described as: B A. cancers present at birth B. neoplasms composed of a mix of tissues from 3 germ layers C. neoplasms composed of undifferentiated anaplastic cells D. None of these 12) Each of the following may contribute to formation of edema EXCEPT: C A. decreased plasma oncotic pressure B. increased intravascular hydrostatic pressure C. increased serum albumin D. None of these 13) Which of the following would least likely directly lead to anoxic cell injury: C A. carbon monoxide poisoning B. cyanide poisoning C. hypoglycemia D. None of these 14) Hyperacute graft rejection most likely involves: C A. formation of granulomas in the graft B. infiltration of the graft by plasma cells Discipline: ________________________ Page 2 of 61 C. preformed antibodies deposited on graft endothelium D. None of these 15) Unconjugated bilirubin is derived principally from: C A. glucuronyl transferase activity B. toxic liver injury C. breakdown of senescent red blood cells D. None of these 16) Centrilobular necrosis is associated with C A. Halothane B. Thorazine C. Carbon tetrachloride D. None of these 17) In comparison to periportal hepatocytes, centrilobular zones are characterized by: C A. less smooth endoplasmic reticulum B. larger nuclei C. poorer oxygenation D. None of these 18) Which one of the following tests would be most effective in ruling out the presence of active hepatocellular disease? A A. Serum alanine aminotransferase (ALT) B. Serum total bilirubin C. cell surface markers D. None of these 19) Serum concentration is increased when destruction of erythrocytes is increased A A. Unconjugated bilirubin B. Conjugated bilirubin C. Both D. None of these 20) Markedly increased concentration responsible for kernicterus in hemolytic disease of the newborn. A A. Unconjugated bilirubin B. Conjugated bilirubin C. Both D. None of these 21) Predominantly unconjugated hyperbilirubinemia is typical of: A A. intravascular hemolysis B. carcinoma of common bile ducts C. carcinoma of gall bladder D. None of these 22) Which one of the following are cardinal features of granulation tissue? C A. Abundant collagen B. Proliferating macrophages and lymphocytes C. Proliferating capillaries and fibroblasts D. None of these [Show More]

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