Georgia State University > Biology > Bio 4930, Exam 2 (ALREADY GRADED A)

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Biol 4930/6930 Exam 2. Spring 1.Please explain why PPARγ agonists are used to treat diabetes, what are the benefits and side effects of the drugs and why is that? (30 points). 2a. H... ow PGC1α was identified and how it coordinates with PPARγ in inducing brown adipocyte development? 2b. What is PGC1α’s function in brown fat, liver and muscle? 2c. How PRDM16 was identified and what is PRDM16’s function in regulating brown adipocyte development? You need to incorporate the origin of brown adipocytes in this answer. 3. What is the pathological mechanism in the development of atherosclerosis? What are the currently available drug targets to treat atherosclerosis and why is that? (In terms of the answers for drug targets, you need to incorporate lipoprotein metabolism pathways into the answers). (30 points). [Show More]

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