BioChemistry > QUESTIONS & ANSWERS > Central Dogma and Genetic Medicine questions and answers grade A+ (All)

Central Dogma and Genetic Medicine questions and answers grade A+

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Procedure As you proceed through the Click & Learn, follow the instructions below and answer the questions in the spaces provided. 1. Let’s review! The central dogma of molecular biology refers t... o the process of gene expression. Write the definition of gene expression in your own words. 2. Click on the “Central Dogma” menu tab at the top of the screen. The table below outlines the steps in eukaryotic gene expression. Click on each tab or scroll through the page and briefly summarize each step below. Gene expression is how genes are given directions to DNA to make proteins and other molecules Gene Expression Steps Molecules Involved What molecules and proteins are involved in this step? Summary What happens during this step? Transcription DNA, RNA Polymerase, Intron, Exon RNA polymerase transcribes a gene’s DNA into an RNA transcript with a complementary sequence. RNA Splicing Intron, exon, spliceosome RNA transcript is edited through splicing by the spliceosome trimming out the introns and splicing exons together to produce mRNA. mRNA Transport mRNA mRNA is transported from nucleus to the cytoplasm Translation mRNA,polypeptide, RIbosome translates 3. Mutations in the DNA can affect the structure and function of proteins. Some mutations may even cause genetic diseases. Scientists and doctors can intervene at different points during gene expression to develop treatments for such genetic diseases—or genetic medicine. Let’s learn about the genetic medicines that are being developed Select the “Genetic Medicine” tab located on the top right of the screen. Click on the tab corresponding to the genetic medicine(s) that your instructor assigns to you, or scroll through the interactive and click on the pink “+” sign labeled with that genetic medicine. Read the “Genetic Medicine” tab material, watch the video, and read the information in the “Learn more” link. Then, complete the appropriate row(s) below. ribosome, tRNA mRNA into amino acids after they are brought by tRNA and added into a polypeptide chain. Protein Processing Polypeptide chain The polypeptide chain is folded and assembled into a 3D prote [Show More]

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