NURS 6630 / NURS6630 Midterm Exam Study Guide : Psychopharmacologic Approaches to Treatment of Psychopathology - Walden

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NURS 6630 - Psychopharmacologic Approaches to Treatment of Psychopathology Midterm Exam Study Guide Midterm Exam Study Guide These two neuron types have abundant Alpha 2 receptors: - Noradrenergi... c and Serotonergic When stimulated Alpha 2 receptors inhibit the activity of the presynaptic neuron and decrease the release of these two neurotransmitters: - Norepinephrine and Serotonin Six common Atypical Antidepressants used for individuals that did not respond to other antidepressants: - mirtazapine, trazadone, nefazodone, vilazodone, vortioxetine, bupropion This antidepressant effects Alpha 2 receptors, 5-HT2A receptors, 5-HT3A receptors, and Histamine H1 receptors: - mirtazapine The primary antidepressant action of this drug comes from inhibition of the Alpha 2 receptors, which reduces the inhibition of the synaptic neuron, and thus increases Norepinephrine and Serotonin release - mirtazapine As a Serotonin Antagonist, this Atypical Antidepressant blocks 5-HT2A and 5-HT3A receptors to increase the amount of Serotonin available to bind to 5-HT1A receptors which are more strongly linked to depression: - mirtazapine Mirtazapine's inhibition of 5-HT3A receptors reduces: - nausea and vomiting Mirtazapine's inhibition of Histamine H1 receptors causes: - sedation (could be desirable side effect for depressed individuals with insomnia) [Show More]

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