Walden University -NURS-6630: Approaches to Treatments: Initial Post (Week 3: The Impact of Ethnicity on Antidepressant Therapy) Case # 29- The depressed man who thought he was out of options. Week 3 Discussion Board.

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Walden University -NURS-6630: Approaches to Treatments: Initial Post (Week 3: The Impact of Ethnicity on Antidepressant Therapy) Case # 29- The depressed man who thought he was out of options. Week 3 ... Discussion Board. • List three questions you might ask the patient if he or she were in your office. Provide a rationale for why you might ask these questions. • Identify people in the patient’s life you would need to speak to or get feedback from to further assess the patient’s situation. Include specific questions you might ask these people and why. • Explain what physical exams and diagnostic tests would be appropriate for the patient and how the results would be used. • List three differential diagnoses for the patient. Identify the one that you think is most likely and explain why. • List two pharmacologic agents and their dosing that would be appropriate for the patient’s anti-depressant therapy based on pharmacokinetics and pharmacodynamics. From a mechanism of action perspective, provide a rationale for why you might choose one agent over the other. • For the drug therapy, you select, identify any contraindications to use or alterations in dosing that may need to be considered based on the client’s ethnicity. Discuss why the contraindication/alteration you identify exists. That is, what would be problematic with the use of this drug in individuals of other ethnicities? • If your assigned case includes “checkpoints” (i.e., follow-up data at week 4, 8, 12, etc.), indicate any therapeutic changes that you might make based on the data provided. • Explain “lessons learned” from this case study, including how you might apply this case to your own practice when providing care to patients with similar clinical presentations References: Alsofyani, A. H., Alharbi, A. M. M., Alanazi, A. B. N., Alasous, K. A. A., Ageeli, R. A., ALZahrani, A. A. M., … Ahmad, G. M. (2017). Correlation between Vitamin D Deficiency and Depression. Egyptian Journal of Hospital Medicine, 69(8), 3134–1343. https://doi-org.ezp.waldenulibrary.org/10.12816/0042865 American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author. Dayan, C. M., & Panicker, V. (2013). Hypothyroidism and depression. European thyroid journal, 2(3), 168-79. Effexor. (2007). Rx only. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/020151s046,020699s075lbl.pdf Franklin, R., Zorowitz, S., Corse, A. K., Widge, A. S., & Deckersbach, T. (2015). Lurasidone for the treatment of bipolar depression: an evidence-based review. Neuropsychiatric disease and treatment, 11, 2143-52. doi:10.2147/NDT.S50961 Hage, M. P., & Azar, S. T. (2011). The Link between Thyroid Function and Depression. Journal of thyroid research, 2012, 590648. Latuda. (2011). MPR (Pharmacists’ Edition), (1), 10. Retrieved from https://ezp.waldenulibrary.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edsgea&AN=edsgcl.253388046&site=eds-live&scope=site Lloret-Linares, C., Daali, Y., Chevret, S., Nieto, I., Molière, F., Courtet, P., … Bellivier, F. (2017). Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study). BMC Pharmacology & Toxicology, 18(1), 70. https://doi-org.ezp.waldenulibrary.org/10.1186/s40360-017-0173-2 Lynch, T. (2007). The Effect of Cytochrome P450 Metabolism on Drug Response, Interactions, and Adverse Effects. American Family Physician, 76(3)391-396. Retrieved from https://www.aafp.org/afp/2007/0801/p391.html Stahl, S. M. (2013). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). New York, NY: Cambridge University Press. Stahl, S. M. (2017). The prescriber’s guide (6th ed.). New York, NY: Cambridge University Press. Voican, C. S., Martin, S., Verstuyft, C., Corruble, E., Perlemuter, G., & Colle, R. (2016). Liver Function Test Abnormalities in Depressed Patients Treated with Antidepressants: A Real-World Systematic Observational Study in Psychiatric Settings. PLoS ONE, 11(5), 1. Retrieved from https://ezp.waldenulibrary.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edb&AN=115293329&site=eds-live&scope=site [Show More]

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