Oxford Handbook of Oncology Fourth edition Edited by Jim Cassidy Global Head of Translational Medicine (Oncology), Hoffmann La-Roche, USA Donald Bissett Consultant in Clinical Oncology, Aberdeen Royal Infirmary, Aberdeen Roy A. J. Spence OBE Consultant Surgeon, Belfast Trust, Honorary Professor, Queens University, Belfast, Honorary Professor, University of Ulster Miranda Payne Specialist Registrar in Medical Oncology, Oxford Radcliffe NHS Trust, Oxford Gareth Morris-Stiff Staff Surgeon, Cleveland Clinic, Cleveland, USA; Associate Professor, Lerner College of Medicine, Case Western Reserve University, Cleveland, USA

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Oxford Handbook of Oncology Fourth edition Edited by Jim Cassidy Global Head of Translational Medicine (Oncology), Hoffmann La-Roche, USA Donald Bissett Consultant in Clinical Oncology, ... Aberdeen Royal Infirmary, Aberdeen Roy A. J. Spence OBE Consultant Surgeon, Belfast Trust, Honorary Professor, Queens University, Belfast, Honorary Professor, University of Ulster Miranda Payne Specialist Registrar in Medical Oncology, Oxford Radcliffe NHS Trust, Oxford Gareth Morris-Stiff Staff Surgeon, Cleveland Clinic, Cleveland, USA; Associate Professor, Lerner College of Medicine, Case Western Reserve University, Cleveland, USA Part 1 Background  1 Aetiology and epidemiology  3 2 The genetics of cancer  17 3 Surgical oncology  31 Part 2 Principles of treatment  4 Principles of radiation oncology  49 5 Principles of chemotherapy  83 6 Principles of symptom control in palliative care  111 7 Late effects of chemotherapy and radiotherapy   157 8 Hormone therapy  169 9 Targeted and biological therapies  179 Part 3 Clinical trials, cancer prevention, and screening  10 Clinical trials  199 11 Cancer prevention  203 12 Population screening for cancer  217 Part 4 Specific types of cancer  13 Thoracic malignancies  225 14 Breast cancer  261 15 Colorectal cancer  16 Anal cancer  311 17 Upper gastrointestinal cancer  317 18 Endocrine cancers  381 19 Genitourinary cancers  403 20 Gynaecological cancers  445 21 Head and neck cancers  467 22 Tumours of the central nervous system  495 23 Skin cancers  523 24 Haematological malignancies  549 25 Bone and soft tissue malignancies  603 26 Malignancy of unknown primary  629 27 Paraneoplastic syndromes  645 28 AIDS-related malignancies  655 29 Childhood cancers presenting in adults  671 Part 5 Emergencies in oncology  30 Spinal cord compression and bone marrow suppression  681 31 Overview of acute oncology  691 32 Superior vena cava obstruction and raised intracranial pressure  695 33 Airway obstruction  703 34 Thromboembolic and cardiac emergencies  711 35 Obstruction  719 36 Biochemical crises  731 37 Complications of long-term central venous lines and chemotherapy extravasation  Part 6 The way forward  38 Novel therapeutic strategies  749 39 Gene therapy and genetic immunotherapy for cancer  759 40 Biomarkers and cancer  773 Part 7 Appendices  Appendix 1 NCIC common toxicity criteria (CTC) grading system (March 1998, revised) 785 Appendix 2 Nomogram for the determination of body surface area 853 Appendix 3 Performance status 855 Appendix 4 Support agencies’ addresses and websites [Show More]

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