NR 566 Final Exam Study Guide: Week 5, 6, 7 & 8- Advanced Pharmacology for Care of the Family - 2021/2022

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566 Final Exam Study Guide Week 5 Prevention of osteoporosis with hormone replacement therapy (p. 433) Hormone therapy (HT) reduces postmenopausal bone loss & thereby decreases the risk for osteopo... rosis & related fractures. Unfortunately, when HT is stopped, bone mass rapidly decreases by approximately 12%. Hence to maintain bone health, HT must continue lifelong. As a result, the risk for harm is increased. Accordingly, alternative treatments are preferred. Effective alternatives to HT include raloxifene (Evista) & bisphosphonates like alendronate (Fosamax), calcitonin (Miacalcin), & teriparatide (Forteo). All patients should practice primary prevention of bone loss by ensuring adequate intake of calcium & vitamin D, performing regular weight-bearing exercise, & avoiding smoking & excessive alcohol use. When and when not to use progestin for hormone replacement therapy and why (pp. 430-433) Goals for noncontraceptive uses of progestins are to counteract endometrial hyperplasia caused by unopposed estrogen during hormone therapy; management of dysfunctional uterine bleeding, amenorrhea, & endometriosis; & support of pregnancy in women with corpus luteum deficiency. Progestins are also used in in vitro fertilization cycles & to prevent prematurity in women at high risk for preterm birth. [Show More]

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