NR 508 Advanced Pharmacology Week 5 Quiz/Latest 2022/ Graded A

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Preferred oral agent for DM type 2 (ANS- metformin Vitamin deficiency associated with metformin (ANS- B12 Adverse effect of oral diabetes meds (ANS- n/v/d, flatulence, myalgia, HA. Some ca... use weight gain. Lactic acidosis (metformin) Risk with SGLT2 inhibitors (ANS- amputations, acidosis, yeast/mycotic infections, renal injury, hyperkalemia Preferred antihypertensive for African American (ANS- CCB and ARB Preferred antihypertensive with chronic kidney disease (ANS- ACE/ARB Use and side effect of acetazolamide (ANS- Treatment of open angle glaucoma and acute mountain sickness. Side effect - can cause metabolic acidosis. use and side effect of eplerenone (ANS- Aldosterone agonist. For treatment of moderate to severe HF with reduced EF. Can cause hyperkalemia. Monitor renal function. use and side effect of spironolactone (ANS- Add to ACE and loop in treatment of severe CHF. Side effect - hypokalemia (dose dependent) use and side effect of triamterene (ANS- Weak diuretic. Also interferes with bicarbonate reabsorption and causes bicarb loss in urine. Used in treatment of severe metabolic alkalosis. Excessive loss can cause metabolic acidosis. Therapeutic use of mannitol (ANS- Osmotic diuretic. Reduce intracranial pressure or intraocular pressure in glaucoma therapeutic use of acetazolamide (ANS- treatment of open angle glaucoma and acute mountain sickness MOA of eplerenone (ANS- Competitively inhibit aldosterone receptor. Useful in tx of cirrhosis, ascites and advance HF Diuretic to use in chronic calcium stones (ANS- Thiazide Most effective diuretic for HTN, CHF and renal failure (ANS- loop diuretics Which diuretic is a mineralcorticoid agonist (ANS- spironolactone Carbonic anhydrase inhibitor used to treat altitude sickness (ANS- acetazolamide Fendoldopam MOA and use (ANS- Rapid acting arteriolar vasodilator. Dopamine 1 receptor agonist. Used for treatment of malignant hypertension. Adverse effect of hydralazine (ANS- lupus like syndrome. Palps, n/v/d, HA, constipation (common). Tachy, paresthesias, paralytic ileus, blood dyscrasia, abn LFT, myalgia (serious). BB with alpha blocking an non-selective BB action (ANS- labetolol and carvedilol MOA of alpha methyldopa (ANS- stimulate central inhibitory alpha adrenergic receptors. Inhibit sympathetic cardioaccelerator and vasoconstrictor centers. Results in reduced sympathetic outflow from CNS causing decreased peripheral resistance, renal vascular resistance HR and BP. Vasodilating antihypertensive that promotes hair growth (ANS- monoxidil Prazosin MOA, contraindications and adverse effect (ANS- 1st dose syncope and hyoptension MOA of esmolol (brevibloc) (ANS- Beta blocker. Indication: intraoperative hypertension and arrhythmia. Alternate med for ACEI cough (ANS- ARB [Show More]

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