HMX Immunology > QUESTIONS & ANSWERS > HMX Immunology Final Exam Study Guide 2023 with Complete Solution (All)

HMX Immunology Final Exam Study Guide 2023 with Complete Solution

Document Content and Description Below

HMX Immunology Final Exam Study Guide 2023 with Complete Solution Tissue resident sentinel cells include (3 types) -✔✔ Dendritic cells, macrophages, and mast cells Circulating leukocytes in... volved in innate response (2 types) -✔✔ Monocytes and neutrophils Phagocytic immune cells (2 types) -✔✔ Macrophages and neutrophils Difference between macrophages and neutrophils? -✔✔ Neutrophils are short lived and will undergo apoptosis after eating a microbe; macrophages are longer-lived and will eat apoptotic cells and waste General cytokine role in innate immune response (and what cells release them?) -✔✔ Released by dendritic cells, macrophages, and mast cells. Pro-inflammatory molecules that interact with blood vessel endothelium to recruit circulating leukocytes, fluid, and proteins into tissue Which tissue-resident sentinel cell will release histamine upon activation? -✔✔ Mast cell Cytokines promote up-regulation of what kind of molecule within blood vessel walls? -✔✔ Adhesion molecules E-Selectin -✔✔ An adhesion molecule that helps to slow down circulating leukocytes in innate immune response (low-affinity interaction) E-Selectin Ligand -✔✔ A ligand expressed by circulating leukocytes that helps them stick to blood vessel endothelium in innate immune response ICAM-1 -✔✔ An adhesion molecule that helps circulating leukocytes bind to blood vessel endothelium in innate immune response (high-affinity interaction) Integrins (and the name of a specific one) -✔✔ A class of adhesion molecules expressed on circulating leukocytes; LFA-1 binds to ICAM-1 in a high affinity interaction during the innate inflammatory response Stable Arrest -✔✔ When a circulating leukocyte comes to a stop within the endothelium thanks to adhesion molecule interactions and can enter the tissue Pus -✔✔ Comprised of fluid and apoptotic cells/waste as a result of an inflammatory response (DNA, dead bacteria, apoptotic neutrophils) Psoriasis overview -✔✔ Autoimmune disease that can cause skin plaques and arthritis; Skin plaques are caused by immune cells migrating into the skin and initiating an inflammatory response Psoriasis risk factors -✔✔ History of strep infections, skin injury, first degree relative with psoriasis TNF-alpha in psoriasis -✔✔ A pro-inflammatory cytokine expressed in psoriasis that recruits immune cells into the skin and also acts directly on epithelial cells to produce thickened/raised patches Psoriasis treatment (biologics) -✔✔ Target the pro-inflammatory cytokine TNF-alpha and therefore prevent the expression of adhesion molecules on endothelial cells and prevent TNF-alpha from acting directly on epithelial cells Possible side effects of medications that block adhesion molecules -✔✔ Susceptibility to infection due to inhibiting leukocyte entry into tissue Most abundant leukocyte -✔✔ Neutrophils What kind of infections are neutrophils particularly effective against? -✔✔ Extracellular bacterial infections Plasmacytoid dendritic cell -✔✔ A type of sentinel cell that detects viruses and releases type 1 interferons Type 1 Interferons (Type 1 IFNs) function and the cell that is most efficient at producing them -✔✔ Group of cytokines that activate the antiviral state during viral infection; Plasmacytoid dendritic cells [Show More]

Last updated: 1 year ago

Preview 1 out of 17 pages

Add to cart

Instant download

We Accept:

We Accept
document-preview

Buy this document to get the full access instantly

Instant Download Access after purchase

Add to cart

Instant download

We Accept:

We Accept

Reviews( 0 )

$9.00

Add to cart

We Accept:

We Accept

Instant download

Can't find what you want? Try our AI powered Search

OR

REQUEST DOCUMENT
67
0

Document information


Connected school, study & course


About the document


Uploaded On

May 17, 2023

Number of pages

17

Written in

Seller


seller-icon
Prof.Pierro

Member since 3 years

245 Documents Sold


Additional information

This document has been written for:

Uploaded

May 17, 2023

Downloads

 0

Views

 67

Document Keyword Tags

What is Browsegrades

In Browsegrades, a student can earn by offering help to other student. Students can help other students with materials by upploading their notes and earn money.

We are here to help

We're available through e-mail, Twitter, Facebook, and live chat.
 FAQ
 Questions? Leave a message!

Follow us on
 Twitter

Copyright © Browsegrades · High quality services·