BioChemistry > EXAM > Biochemistry USMLE Step 1: Questions & Answers: Latest Updated A+ Solution (All)
Achondroplasia involves what defect? (Ans- Cell-signaling defect of fibroblast growth factor (FGF) receptor 3 Marfan's syndrome involves a mutation in what? (Ans- Fibrillin gene Nucleoside +... phosphate= ? (Ans- Nucleotide Adenine and Guanine are in what type of nucleic acid? (Ans- Purines Cytosine, Uracil and Thyamine arein what kind of nucleic acid? (Ans- Pyrimidines Xanthine, hypoxanthine and uric acid are all what type of base? (Ans- Purine How many hydrogen bonds are found between Guanine and Cytosine? (Ans- 3 Chargaff's ruledictates that the percent of adenine in a DNA molecule is = to the % of _____ in a DNA molecule. (Ans- thyamine What is the rate limiting step in Purine de novo synthesis? (Ans- PRPP step via glutamin PRPP amidotranferase PRPP amidotransferase inhibited by what downstream products in purine synthesis? (Ans- IMP, GMP, AMP and puring analogs Allopurinola and 6-mercaptopurine What are the required cofactors for purine de novo synthesis? (Ans- THF, glutamine, glycine, aspartate, CO2 [Show More]
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