*NURSING > EXAM > 2024 CPPS 303 - Reproduction 4 ( Fertilization and Pregnancy ) Complete Questions & Answers (Solved) (All)
1. Where does fertilization occur Answer: In the ampulla of the fallopian tube - upper third of the fallopian tube 2. How long does it take for the egg to travel from the place of fertilization tot... he uterus for implantation? Answer: 7 days 3. Capacitation Answer: Once in the female reproductive tract, the protective coat on spermhead is removed - It allows the head to penetrate the zona pellucida - Capacitation allows the acrosomal enzymes to be released later 4. Acrosome Answer: The end of the head of sperm 5. Components of the zona pellucida Answer: 3 glycoprotein layers - ZP1(outer), ZP2, ZP3(inner) 6. Acrosomal Reaction Answer: 1) Receptors on the sperm head bind to ZP3 2) A rise in Ca2+ inside the sperm will trigger the release of the acrosomal contents into the oocyte 7. 8 Steps in fertilization Answer: 1) Sperm head attaches ti zona pellucida - Receptors on the PM of the sperm bind to ZP3, triggering acrosomal reaction 2) Acrosomal reaction occurs - Increase in Ca2+ causes acrosomal contents to be expelled into oocyte 3) Hydrolyzing enzymes in the acrosomal cap facilitate the sperm to penetrate the zona pellucida 4) Cell membranes of sperm and oocyte fuse - IP3 is formed, causing Ca2+ release from internal stores 5) Increase in Ca2+ triggers oocytes 2nd meiotic division and cortical reaction - Granules exocytose and cause the zona pellucida to harden [Show More]
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