NR 565 Pharm Midterm Exam (Latest 2023 - 2024) New Full Questions and Answers ( Included ) 100% Correct

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1. CYP2D6: Need to increase doses of SSRI, beta blockers etc. Codeine can be deadly 2. CYP2C9: Decrease warfarin dose Test for gene VCORC1 mutation 3. CYP3A4: Decreases elimination Increase toxic... ity of Amio 4. Schedule I: no accepted medical use in the US it may not be prescribed. heroin, various opium derivatives,hallucinogenic substances 5. Schedule II: No refills, no telephone orders Narcotics, Stimulants, Depressants 6. Schedule III: Drugs in this category are considered to be at moderate or low risk for physical dependence, and with current reasons for medical use Anabolic steroids, most barbituates and ketamine Must prescribe every 6 months, can be by phone 7. Schedule IV: Abuse potential exists, but lessthan Sch III.Examples are:Ambien, Darvocet and Lorazepam 8. ScheduleV: Not always necessary to have a prescription Loperamide, diphenoxylate and cough medicine with less than 200mg/100 ml pregabalin 9. Preclinical research: Research of drug potential, animal testing, preparation for human testing 10. Phase I: Initial clinical safety studies in humans. May be as few as 10 subjects, often healthy volunteers 11. Phase II: The study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety 12. Phase III: The study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely 13. Phase IV: A study conducted after a drug has been shown to work and has been granted a license (post-marketing surveillance study) [Show More]

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