Erika Thompson Microbiology with Lab 204 Disease Presentation

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bacteria  Bacterial urease (Proteus) splits urea –NH4 ion alkalinizes urine with loss of acid pH– stone formation– obstruction and survival of bacteria within stones resisting eradication ...  Gram-negative edotoxin decreases ureteral peristalsis  Hemolysin damages renal tubular epithelium and promotes invasive infeciton  Aerobactin of E. coli promote iron accumulation for bacterial replication  Escherichia coli strains expressing O-antigens cause high proportion of infections  Capsular antigen of E. coli associated with clinical serverity (antiphagocytic)  P-fimbriae enhance attachment of E. coli to uroepithelial cells  Motle bacteria ascend the ureter against urine flow • UTIs are considered to be the most common bacteria infection • Most common bacterial infection that is found to affect the elderly and the most frequent source of bacteremia • The incidence ration of UTIs in middle-aged women to men is 30:1 • Men’s urethral length is longer than women, making UTIs less common. It helps prevent bacterial colonization within the bladder. • The risk of UTIs in women is increases after menopause • After an infection, recurring infections are usually reinfections [Show More]

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