Central Dogma and Genetic Medicine. STUDENT OVERVIEW. worksheet complements the Process. BioInteractive.

Document Content and Description Below

OVERVIEW This worksheet complements the Central Dogma and Genetic Medicine Click & Learn. PROCEDURE As you proceed through the Click & Learn, follow the instructions below and answer the question s in... the spaces provided. 1. Let’s review! The central dogma of molecular biology refers to the process of gene expression. Write the definition of gene expression in your own words. 2. Click on the “Central Dogma” menu tab at the top of the screen. The table below outlines the steps in eukaryotic gene expression. Click on each tab or scroll through the page and briefly summarize each step below. Gene Expression Steps Molecules Involved What molecules and proteins are involved in this step? Summary What happens during this step? Transcription RNA Splicing mRNA Transport Translation Protein Processing 3. Mutations in the DNA can affect the structure and function of proteins. Some mutations may even cause genetic diseases. Scientists and doctors can intervene at different points during gene expression to develop treatments for such genetic diseases—or genetic medicine. Let’s learn about the genetic medicines that are being developed. Select the “Genetic Medicine” tab located on the top right of the screen. Click on the tab corresponding to the genetic medicine(s) that your instructor assigns to you, or scroll through the interactive and click on the pink “+” sign labeled with that genetic medicine. Read the “Genetic Medicine” tab material, watch the video, and read the information in the “Learn more” link. Then, complete the appropriate row(s) below. Genetic Medicine Short Summary Write a one-sentence summary of how this genetic medicine works. Detailed Description Describe how this genetic medicine would be used to treat a genetic disease. (For example, mention how it would fix the disease-causing mutation and/or result in a functioning protein.) CRISPR- Cas9 Gene Therapy Gene Switches Exon Skipping RNA Interference Small Molecule [Show More]

Last updated: 1 year ago

Preview 1 out of 4 pages