NUR 2474 / NR2474 Pharmacology for Professional Nursing Final Exam Review | Already Rated A | Latest 2021 / 2022 | Rasmussen College You will need to know the following things about the medication li... sted: 1. Ibuprofen a. Classification: NSAID b. Therapeutic use: • Inflammation suppression • Analgesia for mild to moderate pain • Fever reduction c. Adverse Drug Reactions: Gastric upset, heartburn, nausea, gastric ulceration • Bleeding (less with non-aspirin NSAIDs) • Kidney dysfunction d. Interventions: For clients at high risk for gastric bleeding, recommend a proton pump inhibitor, monitor intake and output, monitor signs of MI e. Administration: Oral f. Client Instructions: Take with food, milk, or 8 oz of water to minimize gastrointestinal effects. • Avoid alcohol. • Report persistent gastric irritation and signs of bleeding. • Report any unusual or prolonged bleeding. • Report changes in urine output, weight gain, or signs of fluid retention such as edema or bloating. • Report ringing or buzzing in the ears, sweating, headache, and dizziness. g. Contraindications: Teratogenic • Hypersensitivity to aspirin and other NSAIDS • Peptic ulcer disease • Bleeding disorders (hemophilia, vitamin K deficiency) h. Precautions: Older adults • Cigarette smoking • Alcohol use disorder • Helicobacter pylori infection • Heart failure • Hypertension i. Interactions: ACE inhibitors and angiotensin receptor blockers, Anticoagulants, glucocorticoids, and alcohol 2. Celecoxib (Celebrex) a. Classification: second generation NSAID b. Therapeutic use: Inflammation suppression, fever reduction c. Adverse Drug Reactions: gastric upset, heartburn, nausea, kidney dysfunction, cardiovascular d. Interventions: Monitor for and repo rt gastric upset, heartburn, nausea, diarrhea, or GI bleeding, monitor I and Os e. Administration: Oral f. Client Instructions: • Take with food, milk, or 8 oz of water • Avoid alcohol. • Report persistent gastric irritation and signs of bleeding. g. Contraindications: Severe hepatic impairment • Advanced kidney disease, anemia, h. Precautions: • Alcohol use disorder • Heart failure • Diabetes mellitus • Hypertension 3. Acetaminophen (Tylenol) a. Therapeutic use: fever, mild to moderate pain b. Adverse Drug Reactions: Liver damage (overdose) • Hypertension c. Interventions: Monitor for early symptoms of overdose/poisoning, BP d. Administration: Orally e. Client Instructions: Do not exceed 4 g/day (adults). • Report any abdominal discomfort, nausea, vomiting, sweating, or diarrhea immediately. f. Contraindications: Alcohol use disorder g. Precautions: Anemia • Immunosuppression • Hepatic or kidney disease h. Interactions: Alcohol increases the risk of liver injury, warfarin 4. Tramadol (Ultram) a. Classification: Centrally acting nonopioids b. Therapeutic use: Moderate to moderately severe pain c. Adverse Drug Reactions: Sedation, dizziness • Headache, nausea, vomiting, constipation, urinary retention d. Interventions: Monitor clients when ambulating., give with food, monitor for urinary retention e. Administration: Oral, IV f. Client Instructions: Do not take prior to driving or activities requiring mental alertness. • Sit or lie down if feeling lightheaded. • Change positions gradually. • Increase fluid and fiber intake g. Contraindications: S • Acute intoxication with alcohol, opioids, psychotropic drugs • Seizure disorders • Respiratory depression h. Precautions: Substance abuse history • Liver or kidney disease, older adults i. Interactions: MAOI SSRI 5. Morphine [Show More]
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