WGU C785 Biochemistry Unit Questions (Latest 2023 - 2024) Actual Questions and Answers 100% Correct

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1. Which level of protein structure is disrupted through the hydrolysis ofpeptide bonds? Quaternary Tertiary Primary Secondary Answer: Primary The primary structure of a protein is the sequenc... e of amino acids held together by peptide bonds. Peptide bonds are formed by dehydration reactions and disrupted by hydrolysis. 2. A mutation in the beta-hemoglobin gene, which results in the replacement of the amino acid glutamate in position 6 with the amino acid valine, leads to the development of sickle cell anemia. The structures of glutamate and valine are shown below. If the beta hemoglobin gene in a patient with sickle-cell anemia were to be edited so that the valine in position 6 was replaced with a different amino acid, which replacement for valine would be expected to have the best clinicaloutcome, in theory, for the patient? (Assume the valine can potentially be replaced with any amino acid other than glutamate.) Answer: The original amino acid ina healthy patient is glutamate, which is negatively charged.The mutated amino acidis valine, which is non-polar. Valine is causing sickle cell anemia. The best amino acid to replace valine so that the patient is healthy again would be the one most likeglutamate, so any negatively charged amino acid. 3. Secondary, tertiary, and quaternary levels of protein structure can all beimpacted by exposing a protein to which treatment? Change of a hydrophobic amino acid to a different hydrophobic amino acidAddition of a reducing agent [Show More]

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