1. A 20-kg patient is currently receiving 52 ml/hr of Lactated Ringer's Solution.The clinician has requested that 2 mg/kg/day of metoclopramide be added tothe bag. Metoclopramide is available as a... 5 mg/ml solution. How many milli- liters do you need to add to a 1 liter bag? Answer: This is definitely a more complicatedcalculation question, but when broken down it is not insurmountable. A 20-kg patient will need 40 mg/day of metoclopramide (20 kg x 2 mg/kg/day) Since the fluid is being administered at an hourly rate, we need to figure out howmuch metoclopramide we are administering per hour. 40 mg/day / (24 hr) = 1.7 mg/hr To determine how much volume of metoclopramide is needed, the following math is performed: 1.7 mg/hr / (52 ml/hr) x (1000 ml)= 32.6 mg (Notice how the units cancel out.) 32.6 mg / (5 mg/ml) = 6.5 ml 2. What quantity of drug is found in 200 mLs of a 10% solution? Answer: 20 grams A 10% solution is equal to 100 mg/mL.The easiest way to remember this conversionis to add a zero to the percentage. (10%= 100 mg/mL, 15% = 150 mg/mL, etc.) If 1 mL is equal to 100 mg, then to find out the quantity of drug in 200 mLs, multiply100 mg X 200 = 20,000 mg.There are 20,000 mg in 200 mLs of a 10% solution. But none of the choices are 20,000 mg.We need to go one step further anddetermine how many grams this is. 1 gram is equal to 1,000 mg. We need to divide the milligrams by 1,000.So, 20,000mg / 1,000 = 20 grams. 3. You want to give a pre-surgical dose of antibiotics to your patient.You have a 1 gram vial of cefoxitin that is reconstituted with 5 mls of sterile water.You wantto give a 20 mg/kg dose to a 25 kg dog. How many mls do you give? Answer: 2.5mL Explanation [Show More]
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